We are a computational biology lab within the Department of Biological Chemistry in the David Geffen School of Medicine and also part of the Computer Science Department, the Interdepartmental Bioinformatics Program, the Broad Stem Cell Research Center, the Jonsson Comprehensive Cancer Center, and the Molecular Biology Institute at UCLA.

The focus of the lab is on developing and applying machine learning methods for the analysis of high-throughput experimental data to address problems in epigenomics and gene regulation. Our research is often conducted in close collaboration with experimental groups. Please see the publications page to learn more about the lab's research.

We are recruiting new members, if interested please see the positions page.

Recent News

  • April 2013: Genome Research publishes online Interplay between chromatin state, regulator binding, and regulatory motifs in six human cell types by Ernst and Kellis. The paper takes the #1 position on the journal's list of 'Top 10 Most Read Articles.'

  • April 2013: ScienceWatch ranks the Ernst et al, Nature 2011 paper #6 for 'What's Hot In Biology' based on recent citation counts.

  • February 2013: Jason is selected as a 2013 Sloan Research Fellow. See press releases from UCLA, the University of California, the Sloan Foundation, and the New York Times ad.

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